Sensors for Chemical and Biological Detection

 

化學和生物檢測的感測器

12月10日(二)

7:30 am Registration and Morning Coffee

Plenary Session

8:20 Chairperson's Remarks

Christopher Hartshorn, PhD, Program Director, Cancer Treatment & Diagnosis, National Institutes of Health; National Cancer Institute

8:30 Predictive Analytics in Digital Diagnostics for Management of Chronic Conditions

Rafael Carbunaru, PhD, Vice President R&D, Boston Scientific

9:00 Regulatory Considerations during Mobile Medical App Development for Commercial and Clinical Trial Use

Mike Benecky, Senior Director, Global Regulatory Affairs in Precision and Digital Medicine, GlaxoSmithKline

Mobile medical apps are defined as medical devices from their intended use. Mobile medical app regulation is health risk-based to balance patient safety and barriers to technological innovation. Medical device patient risk analysis is a critical prerequisite prior to sensor/app inclusion within a clinical trial. Key components of quality management systems for mobile medical apps include: software requirements/specifications, user acceptance testing, software postmarket surveillance, software version control, and medical device adverse event reporting.             

9:30 Nanotechnology, MEMS, Microfluidics for Health 4.0 Hypermobility

Ali Tinazli, PhD, Senior Director & Head, Healthcare & Life Sciences Strategy, Hewlett-Packard, HP Inc., CTO Office

New imperatives of healthcare are focusing on prevention, personalization of diagnostics and treatment, and democratization, including access to everyone, anywhere, anytime at a low cost. The technology convergence in medicine is enabled by the powerful combination of microelectronics, microfluidics, distributed network, and data analytics.

10:00 Networking Coffee Break

10:30 Roundtable Discussions

Innovative Biological Detection and Challenges

11:25 Chairperson's Remarks

Phillip M. Mach, Analytical Chemist, US Army

11:30 Selective and Reversible Biodetection in Complex Matrices - Synergistic Roles of Biology and Electronics

Radislav Potyrailo, PhD, Principal Scientist, Chemical & Biological Sensing Lab, GE Global Research Center

We are developing aptamer-based biosensors to achieve new performance capabilities. Aptamers are single-stranded nucleic acids folded into their 3D conformations governed by their sequence and environmental conditions. Here, we will discuss our progress in three directions. First, we enhance biodetection selectivity in complex environments. Second, we introduce our innovative methodology for selection of aptamers.Third, we introduce the highly desired reversibility of biosensors.

12:00 pm eCoating for Electrochemical Sensors - Addressing a Bottleneck to Commercialisation

Pawan Jolly, PhD, Senior Scientist, Wyss Institute, Harvard University

Affinity-based electrochemical sensors offer great potential for the development of multiplexed point-of-care (POC) diagnostics; however, their commercialization has been limited because these devices rapidly lose sensitivity due to biofouling in complex biological fluids.   Here we describe a simple drop-casting method that may be used to create sensor coatings that provide potent antifouling properties while retaining electrode conductivity in human blood and plasma.

12:30 Sponsored Presentation (Opportunity Available)

1:00 Enjoy Lunch on Your Own

Innovative Biological Detection and Challenges Cont.

1:55 Chairperson's Remarks

Phillip M. Mach, Analytical Chemist, US Army

2:00 FEATURED PRESENTATION: Multifunctional Sensor Platform Enabled by Additive Manufacturing

Mahmooda Sultana, PhD, Associate Branch Head, Instrument Systems Engineering Branch, NASA Goddard Space Flight Center

In this talk, I will discuss our work on multifunctional sensor platform with a suite of environmental sensors fabricated with a variety of nanomaterials using additive manufacturing techniques. The platform is capable of sensing a variety of environmental parameters including pressure, temperature and target gases, and then transmitting the data via a wireless antenna. This technology has numerous space and terrestrial applications.

2:30 Nanotechnology Innovations Converging to Disrupt Multi-Gas Sensing

Sundip R. Doshi, Founder & CEO, AerNos, Inc.

Multiple industries have mission critical needs for affordable, effective multi-gas monitoring capabilities. Breakthroughs in nanotechnology using MEMS circuitry, hybrid nanostructures and signal processing deliver gas sensors that dramatically improve monitoring capabilities. This presentation will use AerNos AerN2S technology to illustrate and explore gas sensor application challenges, including low level detection, size, cross-contamination, calibration, real-time, integration, manufacturing and costs associated with building next generation multi-gas sensors.

3:00 FEATURED PRESENTATION: Introducing High Accuracy Pressure Sensing into the Consumer Medical Space

Robert Robinson, General Manager, Electronic & Gas Sensing Business, Honeywell

With significant advancement in medical technology, many technological firms are beginning to grasp the opportunity to harness real-time medical monitoring from wearables devices. The progression of technology in the medical grade wearable segment is challenging the age-old perception that high accuracy devices should command high prices. This session will discuss how firms can balance between high accuracy features and cost to help them differentiate in the marketplace

3:30 Refreshment Break in the Exhibit Hall with Poster Viewing

4:00 Tutorials

6:00 Welcome Reception in the Exhibit Hall with Poster Viewing

7:00 End of Day

12月11日(三)

8:00 am Registration and Morning Coffee

Plenary Session

8:20 Chairperson's Remarks

Robert Rubino, Senior Director, Research and Development, Integer

8:30 Dexcom's Continuous Glucose Monitoring (CGM) Technology and Its Impact on Diabetes Management, Artificial Pancreas, & Digital Health Systems

Peter Simpson, Vice President of Sensor R&D and Advanced Technology, Dexcom

Recent advances in continuous glucose monitoring (CGM) technology have significantly increased its usability and impact on diabetes management.  CGM's are now widely reimbursed and are rapidly becoming the standard of care for people on intensive insulin therapy.This presentation will provide an overview of Dexcom's CGM sensor technology, its use in digital health and artificial pancreas systems and a preview of our future products.

9:00 Objective Measures for Clinical Assessment and Precise Understanding of Disease Progression

Christopher Hartshorn, PhD, Program Director, Cancer Treatment & Diagnosis, National Institutes of Health; National Cancer Institute

This talk will look at various efforts across the National Institutes of Health attempting to enable more objective measures for out-of-clinic, patient-specific assessment and longitudinal understanding of disease progression in large cohorts.

9:30 Wearable Electrochemical Sensors - Recent Advances

Joseph Wang, Distinguished Professor & Chair, Nanoengineering, University of California, San Diego

This presentation will discuss recent developments in the field of wearable electrochemical sensors integrated directly on the epidermis or within the mouth for various non-invasive biomedical monitoring applications. Particular attention will be given to non-invasive monitoring of metabolites and electrolytes using flexible amperometric and potentiometric sensors, respectively, along with related materials, energy and integration considerations. The preparation and characterization of such wearable electrochemical sensors will be described, along with their current status, future prospects, and challenges. 

10:00 Coffee Break in the Exhibit Hall with Poster Viewing

10:30 pm Roundtable Discussions

Dealing with Biological Threats

11:25 Chairperson's Remarks

Cory Bernhards, PhD, Research Microbiologist, CBR, Defense Threat Reduction Agency

11:30 The BioACER Sensor: Biological Automated Collector/Detector for Expeditionary Reconnaissance

Cory Bernhards, PhD, Research Microbiologist, CBR, Defense Threat Reduction Agency

We are developing the BioACER sensor, which is a completely novel and fully automated device that conducts remote sample collection (while flying through a plume), preparation, identification, and reporting for biological aerosols within 15 minutes. This unmanned device will allow for low cost, rapid, and accurate identification of biological threats, while eliminating the risk of exposure to operators and allowing for early warning to protect both soldiers and civilian populations.

12:00 Nanopore Sequencing for Rapid Identification of Biological Threats in the Field and Biosurveillance

Maria Arevalo, PhD, Research Microbiologist, Defense, Defense Threat Reduction Agency

The warfighter needs quick and relevant information on emerging biological threats that may present themselves in the field. Next-generation sequencing technologies allow for the analyses of whole genomes for unbiased, conclusive identification of pathogens, but can also help to detect and distinguish novel and synthetically modified threats. We are developing rapid sample-to-answer workflows for processing, sequencing, and automated analysis of environmental samples to identify biological threats in the field.

12:30 Sponsored Presentation (Opportunity Available)

1:00 Enjoy Lunch on Your Own

Miniaturized Sensing and Point-of-Care Diagnostics

1:55 Chairperson's Remarks

Cory Bernhards, PhD, Research Microbiologist, CBR, Defense Threat Reduction Agency

2:00 Silicon-Based, Miniaturized Sensing Technologies for Real-Time, Multi-Parameter Monitoring

Winny Tan, PhD, Senior Manager, Strategic Alliances, IMEC USA

Continuous analysis of biological and chemical substances offers great promises for applications such as environmental monitoring, diagnostics, precision agriculture, food analysis, and process analytical tools for monitoring pharmaceutical manufacturing processes. However, if we want to realize these promises, we need to drastically decrease the cost, size and power consumption of current solutions - while increasing their performance. Hence the unique value of semiconductor-based technologies and their opportunities for extreme miniaturization and integration of hardware and software algorithms at the sensor node level. This presentation will give an overview of highly compact, yet extremely sensitive sensor and imaging technologies that can be applied for high-throughput, real-time analysis of biological and chemical substances. Detecting heavy metals, pollutants and even bacteria are all part of our roadmap.

2:30 Biosensors for Use in Point-of-Care Applications

Prasad Pamidi, PhD, Director Sensor Development, Instrumentation Lab, Werfen Company

Biosensors applications are rapidly growing in point-of-care testing. The majority of these sensors are used in single use applications and some of them lack operational simplicity or laboratory quality in accuracy and precision. This presentation will focus on addressing common challenges in developing point of care friendly biosensors and recent options to address such gaps in point-of-care testing.

3:00 pm Transforming Testing with Saliva

Stan Skafidas, PhD, Professor, University of Melbourne; Co-Founder, CTO, MX3

Peak physical and mental performance is dependent upon optimal hydration. The development of the MX3 test strip represents the first commercially available saliva-based electrochemical biosensor for hydration testing, measuring salivary osmolarity (SOSM), a sensitive indicator of hydration status. Using the MX3 test strip and MX3 Lab hydration status can be measured directly from the tongue in seconds, providing laboratory- grade, actionable results for sports and performance and health and wellbeing.

3:30 Refreshment Break in the Exhibit Hall with Poster Viewing

4:00 Tutorials

6:00 End of Day

* 活動內容有可能不事先告知作更動及調整。

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