TSensor R&D for Healthcare Applications




7:30 am Registration and Morning Coffee

Plenary Session

8:00 Chairperson's Remarks

Craig Wohlers, Executive Director, Conferences, Cambridge Innovation Institute

8:10 AI to the Rescue: Curing and Augmenting Brain Capabilities with the Smart Kiwi Nano-Implant

Newton Howard, PhD, Professor Neurocomputation and Neurosurgery, Brain Sciences Foundation, Oxford University; Chairman, Board of Directors, ni2o

Brain Computer Interface technologies are in constant improvement with interaction modalities ranging from non-invasive (EEG, TMS, etc.) to chronically implanted devices. We are presenting here Kiwi, a novel, minimally invasive micro-implant using nanotechnologies to record the electrical activity of neural tissue and stimulate using electrical and optical stimulation modalities. Kiwi micro-implant is operating wirelessly and is coupled to a cutting-edge AI module providing the possibility to detect in real-time neural activity patterns and adjust the stimulation parameters accordingly. This adaptative, minimally invasive and smart BCI opens a new way for personalized therapeutic applications in numerous diseases such as neurodegenerative diseases (Parkinsons, Alzheimers, etc.), mental illnesses (depression, anxiety, etc.) or chronic pain, brain augmentation, and research device.

8:35 PANEL DISCUSSION: Sensor Mergers & Acquisitions: Models for Success and Lessons from Failures

Panel Moderator:

Moderator: Andy Gilicinski, Global Vice President, Research Development & Engineering, Mergers and Acquisitions, SC Johnson & Son

This panel discussion will examine the current landscape of mergers and acquisitions with the sensors and device space. Our panel of experts will discuss the current outlook within the marketplace and will examine past success and failures and how the pitfalls of failure can be avoided.

9:25 Coffee Break in the Exhibit Hall with Poster Viewing

Advanced Biosensor Design, Materials & Engineering

9:55 Chairperson's Remarks

Marcie Black, PhD, CEO, Advanced Silicon Group

10:00 Micro Raman Sensing for Cancer Applications

Gregory Auner, PhD, Paul Strauss Endowed Chair; Professor, Department of Surgery and Biomedical Engineering; Director, Smart Sensors and Integrated Microsystems Program, Wayne State University

Novel approaches toward understanding the evolution of disease can lead to the discovery of biomarkers that will enable better management of disease progression and improve prognostic evaluation. Raman spectroscopy is a promising investigative and diagnostic tool that can assist in uncovering the molecular basis of disease and provide objective, quantifiable molecular information for diagnosis and treatment evaluation. This presentation will review the use of state-of-the-art micro Raman spectroscopy sensing of cancer, utilizing the power of trained Deep Learning algorithms for near instantaneous diagnosis in the OR and clinical setting.

10:30 Engineering in Medical Diagnostics and Therapeutics: New Treatment Options for Gastric Cancer

Anna Radovic, PhD, Associate Professor, Northeastern University

Modern medicine depends on combined efforts of engineers and biologists. We tested a plant metabolite Gallic Acid (GA) as an alternative treatment for gastric cancer, one of the deadliest worldwide. Using MEMS sensors, DNA microchip arrays, and molecular biology techniques we identified the likely target for the treatment and evaluated its efficiency. We demonstrated the GA ability to reverse malignant transformation in cell culture.

11:00 Nanosensors for 30-Second Handheld Pathogen Detection

Lisa Diamond, CEO, Pinpoint Science LLC

Pinpoint Science offers unique nanosensor technology for low-cost detection of viral, bacterial and fungal pathogens in seconds, with detection levels below 500 femtograms/ml. This unique diagnostic platform can use antibodies, oligos, aptamers and nanobodies for rapid, label-free bioelectronic detection and quantification of pathogens in point-of-care settings.

11:30 Electrochemical Sensors and Systems for Wearable and Minimally Invasive Healthcare Applications

Paul Galvin, PhD, Head, ICT for Health Strategic Programs, Tyndall National Institute

This presentation will describe some emerging electrochemical sensors and systems to address the challenges of continuous real-time monitoring of selected biomarkers for wearable and minimally invasive medical devices. Challenges which will be discussed will include sensor and instrumentation design, sensor biocompatibility, how to prevent biofouling impacting on performance, form factor of the system, etc. Some exemplars of the emerging systems will be showcased.

12:00 pm Sponsored Presentation (Opportunity Available)

12:30 Enjoy Lunch on Your Own

Market and the Path to Commercialization

1:25 Chairperson's Remarks

Paul Galvin, PhD, Head, ICT for Health Strategic Programs, Tyndall National Institute

1:30 How the Future of Sensing in Health Will Be Transformed with AI and 5G

John Mattison, MD, Assistant Medical Director, Chief Health Information Officer, Kaiser Permanente; Faculty, Singularity University

Advanced Biosensor Design, Materials & Engineering

2:00 Sensors for Health Analysis from Exhaled Breath

Sterghios A. Moschos, PhD, Associate Professor in Cellular and Molecular Sciences; Director of Research and Innovation; Director of Postgraduate Research, Department of Applied Sciences, Northumbria University

Since breath alcohol measuring devices became handheld, many companies have tried to replicate this success for other conditions and disease- with no success. The problem has proven to be high variability, sample contamination risks, and even sample loss- all contributing to unreliable data, even with 35-pound desktop instruments. We have addressed these three problems specifically by developing a new, handheld breath capture device. Our preliminary data further show that our solution is capable of detecting and analysing microorganisms living deep in the lung, in a fully non-invasive manner. The patent-protected technology has utility beyond human/veterinary healthcare and well-being in the biodefence, environmental monitoring, agritech and food sectors.

2:30 Silicon Nanowire Biosensors

Marcie Black, PhD, CEO, Advanced Silicon Group

We present Advanced Silicon Group’s nanowire biosensor which enables low cost, multiplexed, and rapid detection of proteins and DNA using one test. The nanowires make the sensor more sensitive to its environment allowing detection of dilute solutions.  Our vision is to make diagnostics rapid, easy to use, and low cost so that everyone has access to good healthcare.

3:00 Refreshment Break in the Exhibit Hall with Poster Viewing

3:30 Wearable, Novel, Optical Sensor for Continuous Noninvasive Blood Pressure (cNIBP) Monitoring

Mohan Thanikachalam, Research Assistant Professor, Public Health & Community Medicine, Tufts University

ViTrack™ is a first-of-its-kind, cuff-less, wearable, standalone technology for cNIBP monitoring, which includes a novel optical sensor capable of 3D contact sensing at microscale. The wrist wearable ViTrack™ device captures the spatiotemporal force distribution within the contact region of the skin and utilizes a proprietary new methodology to directly measure (self-calibrate) and continuously track systolic and diastolic BP.

4:00 Health and Wellness through Salivary Diagnostics

Manesh Kalayil Manian, PhD, Research & Development Lead, Traq

Noninvasive approach to monitor individual's physiological and pathological state is one of the most desirable goals in healthcare research. The presence of various disease-signaling biomarkers and ease of sampling and storage makes saliva a useful medium of detection. Traq makes cost efficient, accurate and portable biosensors that can track activity and health data using saliva as a medium in real time. Traq products are designed to go anywhere, giving flexibility of where and when you track personal health and wellness data, decreasing the need for hospital and physician office visits. This powerful solution creates a synergy that can change the way we all approach health. Own Your HealthTM. This presentation overviews the clinical importance of saliva as a diagnostic medium and portrays the current research and technology development in Traq.

4:30 AI Powered Sensing for Next-Generation Health-Tracking

Karim Arabi, PhD, CEO, Atlazo

Sensing and computing have traditionally been separate functions. Recently, we have seen a trend towards integration of sensing and computing, and with the advent of AI, this trend is accelerating. This talk highlights the benefits of sensing and AI integration for voice activation, context awareness and health-tracking applications.

5:00 Close of Summit

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