SELECTBIO Conferences Biodetection & Biosensors Summit 2019

議程



Other Track Agendas

BioDetection and BioSensors Summit 2019  |  BioEngineering Summit 2019  | 


2019年4月1日(一)

08:00

Day 1 of the Event is the BioEngineering Track

2019年4月2日(二)

08:00

Morning Coffee, Pastries and Networking

09:00

Joseph WangKeynote Presentation

Wearable Electrochemical Sensors: Toward Labs on the Skin or in the Mouth
Joseph Wang, Chair of Nanoengineering, SAIC Endowed Professor, Director at Center of Wearable Sensors, University of California-San Diego, United States of America

Wearable sensors have received a major recent attention owing to their considerable promise for monitoring the wearer’s health and wellness. The medical interest for wearable systems arises from the need for monitoring patients over long periods of time. These devices have the potential to continuously collect vital health information from a person’s body and provide this information to them or their healthcare provider in a timely fashion. Such sensing platforms provide new avenues to continuously and non-invasively monitor individuals and can thus tender crucial real-time information regarding a wearer’s health.  This presentation will discuss recent developments in the field of wearable electrochemical sensors integrated directly on the epidermis or within the mouth for various non-invasive biomedical monitoring applications. Particular attention will be given to non-invasive monitoring of metabolites and electrolytes using flexible amperometric and potentiometric sensors, respectively, along with related materials and integration considerations. The preparation and characterization of such wearable electrochemical sensors will be described, along with their current status and future prospects and challenges.

09:45

Soft Electronics For Noninvasive Healthcare: From the Skin to Below the Skin
Sheng Xu, Assistant Professor, University of California, San Diego, United States of America

Soft electronic devices that can acquire vital signs from the human body represent an important trend for healthcare. Combined strategies of materials design and advanced microfabrication allow the integration of a variety of components and devices on a stretchable platform, resulting in systems with minimal constraints on the human body. We have demonstrated a skin-mounted multichannel health monitor that can sense local field potentials, temperature, strain, acceleration, and body orientation. Integrating ultrasonic transducers on this stretchable platform adds a third dimension to the detection range by launching ultrasound waves that reach well underneath the skin. The ultrasound waves allow capturing a wide range of dynamic events in deep tissues such as blood pressure and blood flow waveforms in central arteries and veins. This technology holds profound implications for continuous and noninvasive sensing, diagnosis, and treatment of chronic diseases.

10:15

Small Sensors Go Big: Towards High-Resolution Monitoring of Industrial Fermentations
Helena Junicke, Marie-Curie Researcher, Technical University of Denmark, Denmark

Miniaturized sensors provide new opportunities for industrial fermentation control. In this frequently overlooked application, sensors allow for an improved spatial surveillance of production units, leading to increased performance and lower risk of failure.

10:45

Morning Coffee Break

11:30

Phage Display and Directed Molecular Evolution: The Nobel Prize and Beyond. Impact on Material Engineering and Biosensor Development
Valery Petrenko, Professor, Auburn University, United States of America

Development of phage engineering technology led to construction of a novel type of phage display libraries-collections of nanofiber materials with diverse molecular landscapes accommodated on the surface of phage particles. These new nanomaterials, called “landscape phage,” serve as a huge resource of diagnostic/detection probes and versatile construction materials for preparation of phage-functionalized biosensors. Landscape-phage-derived probes interact with biological threat agents and generate detectable signals as a part of robust and inexpensive molecular recognition interfaces introduced in mobile detection devices. The use of landscape-phage-based interfaces may greatly improve the sensitivity, selectivity, robustness, and longevity of these devices. My talk aims to attract the attention of chemical scientists and bioengineers seeking to develop functionalized materials and use them in different areas of bioscience, medicine, and engineering.

12:15

Sensors for Biosensors: Efficient Strategies Towards Successful Screening and Commercialization
Daria Semenova, Researcher, Technical University of Denmark, Denmark

Novel strategies towards biosensor design optimization based on combining the results of multi-analytical studies together with the mathematical modelling should be integrated. Moreover, the development of the database platforms for the available sensing technologies should be promoted for further progress in biosensorics.

12:45

Networking Lunch

14:00

Netz ArroyoKeynote Presentation

Feedback Control of Plasma Drug Levels Supported by Continuous In-Vivo Measurements
Netz Arroyo, Assistant Professor of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, United States of America

Personalized drug therapy seeks to tailor treatment to the individual, taking into consideration each person’s unique genotype and metabolism to determine a dose that maximizes drug efficacy and avoids toxicity. Realizing this goal has been extremely challenging, however, for two main reasons. First, it is difficult to determine the optimal drug dose for each patient due to our limited understanding of pharmacogenetics and physiology. Second, even the most sophisticated drug delivery approaches fail to account for hour-to-hour fluctuations in an individual’s metabolism driven by changes in health status, diet or drug interactions. Thus, there remains a pressing need for technologies supporting the real-time, in-vivo monitoring of drugs that would enable patient-specific, metabolism-responsive dosing. In response to this need, our laboratory pursues the development of reagentless sensing approaches that support continuous measurement in the body. During this talk, I will describe an electrochemical approach that relies on DNA aptamers to perform real-time monitoring of small molecule targets, and the use of this approach to study pharmacokinetic changes in rats that originate from biological and metabolic variability.

14:45

Highly-Refractive Barium Titanate Microspheres For Low-Cost Resolution Enhancement In Optical Imaging of Living Micro-Organisms
Daniel Migliozzi, Researcher, Ecole Polytechnique Federale de Lausanne, Switzerland

In this work, we performed a systematic study of the increased resolution mediated by highly-refractive microspheres when imaging micro-structures and micro-objects, and we applied this results to the imaging of micro-organisms in aqueous media.

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